Hier die wissenschaftlic he Nachricht dazu
Geschrieben von IT Oma am 13. Januar 2006 10:14:53:
Als Antwort auf: Vogelgrippe-Virus passt sich dem Menschen an geschrieben von IT Oma am 13. Januar 2006 10:05:23:
Virus from one of the patients shows mutations at the receptor-binding site. One of the mutations has been seen previously in viruses isolated from a small outbreak in Hong Kong in 2003 (two cases, one of which was fatal) and from the 2005 outbreak in Viet Nam. Research has indicated that the Hong Kong 2003 viruses bind preferentially to human cell receptors more so than to avian cell receptors. Researchers at the Mill Hill laboratory anticipate that the Turkish virus will also have this characteristic.
The above comments from the WHO update strongly indicate that the polymorphism found in the isolate from the fatal case in Turkey is S227N (also called S223N using H3 numbering). The polymorphism lead to an increased affinity for human receptors and a deceased affinity for avian receptors. Since the same change in receptor binding affinity is expected from the Turkey isolate, the change would be S227N....
...The latest results indicate H5N1 continues to acquire mammalian polymorphisms via recombination, not random mutation, and these acquisitions are leading to more efficient transmission of H5N1 to humans.
- Re:vorsicht ist die mutter der porzellankiste tascha 13.1.2006 19:08 (0)