Superbug Wins Fight Against New Antibiotic Drug

Geschrieben von Mr. Burns am 14. April 2001 11:32:29:

Hallo,

der Text kommt von Rense, ich verzichte diesmal auf eine
kurze Zusammenfasssung, da sind mir zuviele Fremdwörter drin
und ich habe momentan mal wieder keinen Ziugriff auf meine
Bibliothek :-)

P.S.:
Es wundert mich jedoch nicht daß es ausgerechnet in Groß
Britannien passiert daß Viren gegen Antibiotika resisten
werden.

Viele Grüße
Mr. Burns

Superbug Wins Fight Against
New Antibiotic Drug

A new antibiotic launched last year to spearhead the battle
against hospital superbugs has already faced its first defeat
against a resistant strain.

The drug, linezolid, is licensed in the UK for use in patients
who have developed serious illnesses, such as septicaemia, as
a result of bacterial infection resistant to existing drugs such
as MRSA.

It was hailed as a breakthrough, particularly since the
emergence at Glasgow Royal Infirmary of a strain of
staphylococcus resistant to the last-ditch antibiotic,
vancomycin.

But doctors in Chicago who used linezolid on five patients
suffering from infections caused by a vancomycin-resistant
strain of enterococcus faecium had also encountered
resistance to the new drug. In every case, linezolid was
initially successful, but the enterococci eventually became
resistant, and in three cases the patients grew unresponsive to
treatment.

Dr Ronald Gonzales and colleagues, reporting in the Lancet,
admitted that all five patients in their study - one who had
undergone surgery for an aortic aneurysm, and four organ
transplant patients - had received long courses of the drug,
thereby increasing the chances of resistance.

But they recommended that samples of all
vancomycin-resistant enterococci should be tested for
susceptibility before starting on linezolid.

A spokesman for the makers, Pharmacia, said last night:
"This was very much a last-gasp attempt to treat five very
seriously ill patients.

"We are still confident about the drug's role, which is aimed
at minimising the risk of widespread resistance."




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